Introduction
Ipamorelin is a selective growth hormone secretagogue (ghrelin receptor agonist) characterized in classical pharmacological literature. It is supplied here strictly for laboratory research use only.
Chemical and structural summary
Pentapeptide GHS (Aib-His-D-2-Nal-D-Phe-Lys-NH2). CAS 170851-70-4. Lyophilized research material; confirm CoA.
| Catalog name | Ipamorelin |
|---|---|
| Category | GH Axis Research |
| CAS | 170851-70-4 |
| Molecular weight note | About 711.9 g/mol (reference) |
| Documentation | Lot-specific CoA available on request |
Research history and background
Ipamorelin was described as a selective GH secretagogue with relatively low effects on ACTH/cortisol in comparative animal pharmacology relative to some other GHRPs, making it a useful research tool for GH axis studies.
Areas investigated in laboratory and preclinical research
The following themes appear in peer-reviewed literature. Inclusion here means the topic has been studied or reviewed scientifically - not that catalog materials are validated for any endpoint.
- GHS-R1a (ghrelin receptor) pharmacology
- Pituitary GH release models in laboratory animals
- Selectivity profiling versus other growth hormone-releasing peptides
Mechanisms discussed in the literature
Ipamorelin acts as an agonist at the growth hormone secretagogue receptor (ghrelin receptor), stimulating GH release via pathways distinct from GHRH receptor activation. Descriptions reflect research pharmacology, not clinical use guidance for RUO products.
Key published studies and reviews
Prefer primary literature. Open links in a new tab. Always read full papers for methods and limitations.
Known limitations and evidence gaps
Older pharmacological papers do not establish modern clinical approval for research reagents. Combination marketing claims with other GH-axis peptides are not literature conclusions for RUO supply.
Laboratory handling notes
General laboratory practice for lyophilized peptides includes cool, dry storage protected from moisture and light, careful reconstitution with appropriate research diluents, and documentation of lot numbers. See educational guides for process literacy - not product-specific validated stability claims.
- Storage and stability of lyophilized peptides
- Reconstitution best practices for laboratory use
- Reconstitution calculator (concentration and aliquot volume math)
- How to read a Certificate of Analysis
Regulatory status note
Materials sold by VialVibes are Research Use Only. They are not intended for human consumption, clinical administration, or veterinary use, and are not sold as FDA-approved drugs. Where the scientific literature discusses approved medicines or investigational drug programs involving the same active structure class, those regulated products remain distinct from RUO research reagents. See Research Use Only - what it means and the legal RUO policy.