Research reference only — not a catalog item
SS-31
Research context
Isolated-mitochondria experiments with elamipretide (SS-31) measure ADP sensitivity in aged skeletal-muscle mitochondria and uptake through the adenine nucleotide translocator.
What has been studied
- Isolated mitochondria
- Animal physiological readouts
Pharaoh et al. (2023) measured ADP-stimulated responses in isolated skeletal-muscle mitochondria from young and old animals and ADP uptake through the adenine nucleotide translocator after elamipretide (SS-31). The same study recorded heart and skeletal-muscle function in the animal experiments.
These labels restate the setting of the cited paper. They are not new findings and do not describe a catalog material.
Research model areas
- Aged skeletal-muscle mitochondria
- Adenine nucleotide translocator ADP uptake
Selected published literature
What remains uncertain
Limitations
Mitochondrial measurements in aged muscle, and the related animal physiological readouts in the same study, do not establish a human metabolic or cardiac application.
Model areas in the Body Explorer: Metabolic pathway models.