Research reference only — not a catalog item
Orexin-A
Research context
Orexin-A was identified in rat hypothalamus as a ligand for previously orphan receptors, and central administration in rats was followed by measurements of food consumption.
What has been studied
- Rat localization
- Food-intake measurements
Sakurai et al. (1998) identified orexin-A in the rat hypothalamus as a ligand for two orphan receptors and measured food consumption after central administration in rats. The cited work is a localization and feeding-measurement study.
These labels restate the setting of the cited paper. They are not new findings and do not describe a catalog material.
Research model areas
- Rat hypothalamic localization
- Central administration and food-intake measurements
Selected published literature
What remains uncertain
Limitations
Localization and feeding measurements in rats do not establish a human sleep, appetite, or metabolic application.
Model areas in the Body Explorer: Neural signaling models · Metabolic pathway models.