Research reference only — not a catalog item
FOXO4-DRI
Research context
Cell and mouse studies of a FOXO4-derived peptide record senescent-cell viability, p53 localization, and responses in doxorubicin-treated, fast-aging, and naturally aged mice.
What has been studied
- Senescent-cell assays
- Mouse models
Baar et al. (2017) tested a FOXO4-derived peptide in senescent-cell assays that recorded viability and p53 localization. The mouse experiments recorded fitness, coat, and renal measurements in doxorubicin-treated, fast-aging XpdTTD/TTD, and naturally aged mice.
These labels restate the setting of the cited paper. They are not new findings and do not describe a catalog material.
Research model areas
- Senescent-cell viability assays
- Doxorubicin-treated mice
- Fast-aging and naturally aged mice
Selected published literature
What remains uncertain
Limitations
Cell and mouse results are not a human anti-aging application. This entry is not assigned to a Body Explorer area.