Research reference only — not a catalog item
Dihexa
Research context
An APP/PS1 mouse study of dihexa (N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) recorded Morris water-maze performance, neuronal and synaptic-protein measurements, cytokine levels, and PI3K/AKT pathway readouts.
What has been studied
- APP/PS1 mouse study
Sun et al. (2021) administered dihexa orally to APP/PS1 mice and recorded Morris water-maze performance, neuronal and SYP protein measurements, cytokine levels, and PI3K/AKT pathway readouts, including a PI3K-inhibitor comparison.
These labels restate the setting of the cited paper. They are not new findings and do not describe a catalog material.
Research model areas
- APP/PS1 mouse water maze
- Neuronal and SYP protein measurements
- Cytokine and PI3K/AKT readouts
Selected published literature
What remains uncertain
Limitations
These mouse measurements do not establish a human cognitive outcome. A 2014 mechanism paper (PMID 25187433) was retracted in 2025 and is not used as evidence here.
Model areas in the Body Explorer: Neural signaling models.